Gutology Oral Biome Toothpaste
2 months of microbiome support in a 120 ml tube
A fluoride-free toothpaste that helps strengthen enamel, leaves your mouth feeling naturally fresh and supports a balanced oral microbiome - without harsh foaming agents such as SLS. Powered by hydroxyapatite, a mineral inspired by the natural building blocks of your teeth.
- Clinically Proven
- Rebuilds Enamel
- Microbiome-Safe
- Zero SLS & Toxins
- Pause or cancel anytime
- Free shipping
- 30-day money-back guarantee
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How to use
- Brush twice daily as you would with regular toothpaste.
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Will I get cavities without fluoride?
Short answer: fluoride isn't the only way to protect enamel. Gutology is powered by hydroxyapatite one of the most researched fluoride-free ingredients in oral care, and the same mineral your enamel is naturally made of. It's studied for binding to the tooth surface and supporting remineralisation, leaving teeth feeling smooth and clean. It's how thousands have switched to fluoride-free without the compromise.
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Does it foam?
Yes just gently. Instead of SLS, the harsh synthetic foaming agent in most toothpastes, Gutology uses a naturally-derived surfactant. So you still get a light, pleasant lather without the irritation SLS can cause to gums and soft tissue. You'll finish with that smooth, just-brushed feel: a clean you can feel, minus the heavy foam.
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Does it whiten teeth?
Yes gently and naturally. Gutology's hydroxyapatite works by smoothing the enamel surface and filling in micro-defects, which increases the appearance of whiteness over time. It's a gradual, natural brightening your teeth's own colour enhanced not a harsh chemical bleach.
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Is this safe for children?
Yes and it's a popular choice for families. Because Gutology is fluoride-free, it avoids the swallowing concerns associated with fluoride toothpaste, and it's suitable from ages 3+. For younger brushers, we also make a strawberry kids' version same SLS-free formula, in a flavour they'll actually look forward to.
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How is Gutology different from other natural toothpastes?
Most natural toothpastes stop at what they leave out. Gutology Mint Toothpaste is 99.9% natural, SLS-free and powered by hydroxyapatite. Clean ingredients, with proof they work in harmony with your mouth.
Charcoal Dental Floss (Made from Bamboo)
Microbiome-friendly floss made with bamboo and candle tree wax, infused with charcoal to help lift debris from hard to reach areas without harsh ingredients.
Gutology Oral Biome Toothpaste
For over a century, toothpaste has been built to kill bacteria.
Gutology is probacterial: it works with your mouth's bacteria, not against them
The old approach
Traditional toothpastes rely on strong foaming agents and antibacterial ingredients to create that intensely clean feeling. They are literally designed to destroy all bacteria.
The Gutology way
But your mouth contains a whole community of bacteria - and not all bacteria are bad. Using overly harsh ingredients can disrupt its natural balance.
We clean effectively without trying to wipe everything out, helping your mouth feel fresh while supporting its natural microbiome.
There's a better way to brush
The Gutology Approach
Helps strengthen enamel
Made with hydroxyapatite, the mineral your enamel is made from, to help fill microscopic damage and strengthen enamel as you brush.
Kind to your oral microbiome
Certified KIND TO BIOME® and lab-tested to leave your mouth's good bacteria untouched. Microbiome-friendly, not microbiome-stripping.
Gentle on your gums
SLS is the harsh detergent research links to gum irritation, so we leave it out, for a gentle clean that's kind to your gums
The same thinking as your gut
You already feed your gut's good bacteria. Gutology brings that same probacterial thinking to your mouth.
Independent experts view
The oral microbiome matters
For decades, oral care had one goal: kill bacteria. That thinking is changing. Your mouth is a living microbiome, and the balance of good bacteria is what keeps it healthy. Protecting that balance, rather than stripping it, is where modern dentistry is heading, the same shift we already made with gut health
I believe this is the biggest change in oral care in a generation. The evidence is clear: work with the mouth's microbiome, not against it. That's why I recommend a probacterial approach like Gutology.
- Daily Enamel Care
- Fluoride Free
- Clinically Studied ingredients

Your mouth is where your gut health begins
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01
The first ecosystem.
Every time you swallow, thousands of bacteria travel from your mouth to your gut. Your oral microbiome isn't just about your teeth it's the front door to your digestive system.
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The balance that matters
Most toothpaste is built to strip bacteria away the good with the bad. But a healthy mouth isn't a sterile one. When that balance is disrupted, the ecosystem that protects your teeth, gums and breath can't do its job.
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The Gutology approach
We couldn't in good conscience recommend a gut-health routine that ignored the starting line. So we formulated a toothpaste designed to work with your mouth's good bacteria, not strip them and had it independently tested to prove it.
Independently certified microbiome-friendly. Kind to Biome® scored 9.5 / 10. In independent laboratory testing, our formula left the beneficial bacteria of a healthy mouth undisturbed - cleaning without dsirupting the ecosystem your mouth relies on.
Certified KIND TO BIOME®
Cleans your teeth. Leaves your mouth's good bacteria alone.
Your mouth is home to around 700 species of bacteria, and many of them are on your side. Our Mineral and Kids toothpastes clean with hydroxyapatite, the mineral teeth are made of, and both are independently certified oral microbiome friendly.
- 13 mouth bacteria tested against From friendly residents to known troublemakers, by an independent lab for KIND TO BIOME®.
- 9/9 everyday mouth bacteria left undisturbed In lab tests, by both our Mineral and Kids toothpastes.
- Real human mouth samples, not just lab cultures Swabs from healthy volunteers, so we could see the whole community.
Natural Ingredients
No proprietary blends. No hidden fillers.
Full transparency, always.
- No Fluoride
- No SLS
- No Parabens
- No Artificial Flavours
- No Microplastics
- No Triclosan
View full ingredient list (INCI)
Gutology Hydroxyapatite Toothpaste
- Glycerin
- Aqua
- Hydrated Silica
- Hydroxyapatite
- Glycolipids
- Xylitol
- Lactobacillus Ferment
- Cellulose Gum
- Calcium Carbonate
- Mentha Arvensis Leaf Oil
- Stevioside
- Menthol
- Acacia Senegal Gum
- Aroma
- Mentha Piperita Oil
- Eucalyptus Oil
- Limonene
Gutology Kids Toothpaste
- Glycerin
- Hydrated Silica
- Aqua
- Hydroxyapatite
- Xylitol
- Glycolipids
- Aroma
- Cellulose Gum
- Calcium Carbonate
- Citrus Grandis Seed Extract
- Stevioside
- Acacia Senegal Gum
- Ascorbic Acid
- Lactobacillus Ferment
Gutology Liquid Biome+
- Aqua
- Heptyl Glucoside
- Glycerin
- Fructooligosaccharides
- Hydroxyapatite
- Xylitol
- Mentha Arvensis Leaf Oil
- Sodium Phosphate
- Stevioside
- Menthol
- Propanediol
- Cellulose Gum
- Inulin
- Lactic Acid
- Aroma
- Citric Acid
- Sodium Lauroyl Glutamate
- Sorbitan Caprylate
- Tetrasodium Glutamate Diacetate
- Xanthan Gum
- Eucalyptus Oil
- Limonene
- Tartaric Acid
- Gluconic Acid
- Mentha Piperita Oil
Copper Tongue Scraper
- 100% Pure Copper
Charcoal Dental Floss
- Bamboo
- Charcoal
- Mint Essential Oil
- Candelilla Wax
Join over 100,000 people who think differently about oral care.
What started as a microbiome-led toothpaste has grown into a new way of thinking about everyday oral care.
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Gutology was a very easy swap for us as a whole family, I love that I know I am improving my gut health with each brush every day!
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As a biological hygienist, I scrutinise every ingredient and Gutology is the first toothpaste I've confidently recommended to my patients, used myself, and given to my son.
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I recommend this to my patients because I believe in what's inside it, and hydroxyapatite is a big part of that. It's the mineral our enamel is actually made of, and it's at the heart of what Gutology does.
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As a nutritionist, I am always looking for ways to support my own gut as well as my clients'. That's why I use Gutology, it cleans my teeth and mouth without destroying beneficial bacteria and supports my gut microbiome too.
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My little one absolutely loves brushing her teeth now and loves the taste of her toothpaste! Thank you Gutology!
Have concerns? That's okay. You can find all your urgent answers right here.
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Is this toothpaste worth the price?
Absolutely and here’s why:
At 120ml, Gutology’s toothpaste is significantly bigger than many leading natural alternatives, which often come in 75ml tubes. That means more value per use.
We use biomimetic hydroxyapatite a fluoride-free mineral that mirrors the natural structure of enamel and is studied for its role in supporting surface mineral balance.
Stick with it and save. Our subscription model rewards consistency with better pricing no commitment, cancel anytime.
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Do you test for heavy metals?
Your health is our priority. Every batch is independently tested for heavy metals using ICP-MS (Inductively Coupled Plasma Mass Spectrometry) one of the most advanced and sensitive detection methods available.
We test for critical elements including lead, arsenic, mercury, and cadmium, all of which are consistently below detectable limits.
We also screen for other trace elements such as nickel, chromium, cobalt, and zinc and confirm that all results fall well within the EU and UK’s strict safety thresholds for daily exposure.
These results are reviewed by our quality team to ensure the highest standards of purity and safety. -
Is this product vegan and cruelty-free?
Yes, this has been requested by many nutritionists that we work with. We've achieved this by using a vegetable sourced glycerine in our formulation. It is also 100% cruelty-free.
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Allergies
You are responsible for carefully reading any ingredients listed on our website and/or on any packaging, labels and/or leaflets to avoid the risk of allergic or other adverse reactions.
For more information on allergies: click here.
Gutology was one of the easiest swaps I made. No fluoride, no nasties, and it actually supports your oral microbiome. Feels good to know every little change is adding up.
– Vicki