Gutology Oral Biome Toothpaste

2 months of microbiome support in a 120 ml tube

€48
4.65 out of 5 stars1638 Reviews

A fluoride-free toothpaste that helps strengthen enamel, leaves your mouth feeling naturally fresh and supports a balanced oral microbiome - without harsh foaming agents such as SLS. Powered by hydroxyapatite, a mineral inspired by the natural building blocks of your teeth.

  • Clinically Proven
  • Rebuilds Enamel
  • Microbiome-Safe
  • Zero SLS & Toxins
  • Free shipping
  • 30-day money-back guarantee
  • How to use
    1. Brush twice daily as you would with regular toothpaste.
  • Will I get cavities without fluoride?

    Short answer: fluoride isn't the only way to protect enamel. Gutology is powered by hydroxyapatite one of the most researched fluoride-free ingredients in oral care, and the same mineral your enamel is naturally made of. It's studied for binding to the tooth surface and supporting remineralisation, leaving teeth feeling smooth and clean. It's how thousands have switched to fluoride-free without the compromise.

  • Does it foam?

    Yes just gently. Instead of SLS, the harsh synthetic foaming agent in most toothpastes, Gutology uses a naturally-derived surfactant. So you still get a light, pleasant lather without the irritation SLS can cause to gums and soft tissue. You'll finish with that smooth, just-brushed feel: a clean you can feel, minus the heavy foam.

  • Does it whiten teeth?

    Yes gently and naturally. Gutology's hydroxyapatite works by smoothing the enamel surface and filling in micro-defects, which increases the appearance of whiteness over time. It's a gradual, natural brightening your teeth's own colour enhanced not a harsh chemical bleach.

  • Is this safe for children?

    Yes and it's a popular choice for families. Because Gutology is fluoride-free, it avoids the swallowing concerns associated with fluoride toothpaste, and it's suitable from ages 3+. For younger brushers, we also make a strawberry kids' version same SLS-free formula, in a flavour they'll actually look forward to.

  • How is Gutology different from other natural toothpastes?

    Most natural toothpastes stop at what they leave out. Gutology Mint Toothpaste is 99.9% natural, SLS-free and powered by hydroxyapatite. Clean ingredients, with proof they work in harmony with your mouth.

For over a century, toothpaste has been built to kill bacteria.

Gutology is probacterial: it works with your mouth's bacteria, not against them

The old approach

Traditional toothpastes rely on strong foaming agents and antibacterial ingredients to create that intensely clean feeling. They are literally designed to destroy all bacteria.

The Gutology way

But your mouth contains a whole community of bacteria - and not all bacteria are bad. Using overly harsh ingredients can disrupt its natural balance.
We clean effectively without trying to wipe everything out, helping your mouth feel fresh while supporting its natural microbiome.

There's a better way to brush

The Gutology Approach

Helps strengthen enamel

Made with hydroxyapatite, the mineral your enamel is made from, to help fill microscopic damage and strengthen enamel as you brush.

Kind to your oral microbiome

Certified KIND TO BIOME® and lab-tested to leave your mouth's good bacteria untouched. Microbiome-friendly, not microbiome-stripping.

Gentle on your gums

SLS is the harsh detergent research links to gum irritation, so we leave it out, for a gentle clean that's kind to your gums

The same thinking as your gut

You already feed your gut's good bacteria. Gutology brings that same probacterial thinking to your mouth.

Independent experts view

The oral microbiome matters

For decades, oral care had one goal: kill bacteria. That thinking is changing. Your mouth is a living microbiome, and the balance of good bacteria is what keeps it healthy. Protecting that balance, rather than stripping it, is where modern dentistry is heading, the same shift we already made with gut health

Dr Seb Lomas
I believe this is the biggest change in oral care in a generation. The evidence is clear: work with the mouth's microbiome, not against it. That's why I recommend a probacterial approach like Gutology.
Dr Seb Lomas
  • Daily Enamel Care
  • Fluoride Free
  • Clinically Studied ingredients

Your mouth is where your gut health begins

  1. 01

    The first ecosystem.

    Every time you swallow, thousands of bacteria travel from your mouth to your gut. Your oral microbiome isn't just about your teeth it's the front door to your digestive system.

  2. 02

    The balance that matters

    Most toothpaste is built to strip bacteria away the good with the bad. But a healthy mouth isn't a sterile one. When that balance is disrupted, the ecosystem that protects your teeth, gums and breath can't do its job.

  3. 03

    The Gutology approach

    We couldn't in good conscience recommend a gut-health routine that ignored the starting line. So we formulated a toothpaste designed to work with your mouth's good bacteria, not strip them and had it independently tested to prove it.


    Independently certified microbiome-friendly. Kind to Biome® scored 9.5 / 10. In independent laboratory testing, our formula left the beneficial bacteria of a healthy mouth undisturbed - cleaning without dsirupting the ecosystem your mouth relies on.

Certified KIND TO BIOME®

Cleans your teeth. Leaves your mouth's good bacteria alone.

Your mouth is home to around 700 species of bacteria, and many of them are on your side. Our Mineral and Kids toothpastes clean with hydroxyapatite, the mineral teeth are made of, and both are independently certified oral microbiome friendly.

  • 13 mouth bacteria tested against From friendly residents to known troublemakers, by an independent lab for KIND TO BIOME®.
  • 9/9 everyday mouth bacteria left undisturbed In lab tests, by both our Mineral and Kids toothpastes.
  • Real human mouth samples, not just lab cultures Swabs from healthy volunteers, so we could see the whole community.

Natural Ingredients

No proprietary blends. No hidden fillers.
Full transparency, always.

  • No Fluoride
  • No SLS
  • No Parabens
  • No Artificial Flavours
  • No Microplastics
  • No Triclosan
View full ingredient list (INCI)

Gutology Hydroxyapatite Toothpaste

  • Glycerin
  • Aqua
  • Hydrated Silica
  • Hydroxyapatite
  • Glycolipids
  • Xylitol
  • Lactobacillus Ferment
  • Cellulose Gum
  • Calcium Carbonate
  • Mentha Arvensis Leaf Oil
  • Stevioside
  • Menthol
  • Acacia Senegal Gum
  • Aroma
  • Mentha Piperita Oil
  • Eucalyptus Oil
  • Limonene

Gutology Kids Toothpaste

  • Glycerin
  • Hydrated Silica
  • Aqua
  • Hydroxyapatite
  • Xylitol
  • Glycolipids
  • Aroma
  • Cellulose Gum
  • Calcium Carbonate
  • Citrus Grandis Seed Extract
  • Stevioside
  • Acacia Senegal Gum
  • Ascorbic Acid
  • Lactobacillus Ferment

Gutology Liquid Biome+

  • Aqua
  • Heptyl Glucoside
  • Glycerin
  • Fructooligosaccharides
  • Hydroxyapatite
  • Xylitol
  • Mentha Arvensis Leaf Oil
  • Sodium Phosphate
  • Stevioside
  • Menthol
  • Propanediol
  • Cellulose Gum
  • Inulin
  • Lactic Acid
  • Aroma
  • Citric Acid
  • Sodium Lauroyl Glutamate
  • Sorbitan Caprylate
  • Tetrasodium Glutamate Diacetate
  • Xanthan Gum
  • Eucalyptus Oil
  • Limonene
  • Tartaric Acid
  • Gluconic Acid
  • Mentha Piperita Oil

Copper Tongue Scraper

  • 100% Pure Copper

Charcoal Dental Floss

  • Bamboo
  • Charcoal
  • Mint Essential Oil
  • Candelilla Wax

Join over 100,000 people who think differently about oral care.

What started as a microbiome-led toothpaste has grown into a new way of thinking about everyday oral care.

  • Vicki

    Gutology was one of the easiest swaps I made. No fluoride, no nasties, and it actually supports your oral microbiome. Feels good to know every little change is adding up.

    – Vicki

  • Sophie

    Gutology was a very easy swap for us as a whole family, I love that I know I am improving my gut health with each brush every day!

    – Sophie

  • Beverley

    As a biological hygienist, I scrutinise every ingredient and Gutology is the first toothpaste I've confidently recommended to my patients, used myself, and given to my son.

    – Beverley

  • Dr Seb

    I recommend this to my patients because I believe in what's inside it, and hydroxyapatite is a big part of that. It's the mineral our enamel is actually made of, and it's at the heart of what Gutology does.

    – Dr Seb

  • Kayla

    As a nutritionist, I am always looking for ways to support my own gut as well as my clients'. That's why I use Gutology, it cleans my teeth and mouth without destroying beneficial bacteria and supports my gut microbiome too.

    – Kayla

  • Frankie

    My little one absolutely loves brushing her teeth now and loves the taste of her toothpaste! Thank you Gutology!

    – Frankie

Some of the reviews shown are from related products the merchant grouped with this one.
M
Maria M.
I had wanted to try this for some time before I

I had wanted to try this for some time before I bit the bullet and actually purchased it. Took me about 2 weeks to get used to the taste, its not horrible but just different to commercial toothpaste. So glad that I did persevere though, as I have had less gum bleeding and bad breath since using it over the last 10 months. I will never go back to commercial toothpaste or mouth wash! I also plan to buy the set as gifts for Christmas presents thats how much I love this product. Ive introduced my sister who has become a convert as well.

S
Sundy G.
It’s a great toothpaste!

It’s a great toothpaste and I can make the tube last a looooong time
My teeth feel silky smooth and they look whiter too
Xx

H
Helena S.
Worth the extra money

I've been using this healthier and more enamel protective toothpaste enriched with hydroxyapetite since the beginning of Gutology. I wouldn't be without it now because I don't want fluoride in my mouth. I don't go to the dentist - good oral care is my insurance. Worth the extra money.

D
Deborah T.
I have receding gums due to age I also have very

I have receding gums due to age
I also have very thin enamel on my teeth. This is a genetic inheritance from both parents
I have taken the upmost care of my teeth all my life. I have been using your product twice a day for 2 weeks and can't see the slightest improvement.

E
Elad A.
Love it

It tastes and feels good and the tube size offers great value for money.

T
Tina
I feel this is the best product for my teeth health and that of my family's too.

I can't necessarily see any difference to my teeth but I trust the dentists who promote it and feel this is the best product for my teeth health and that of my family's too. It tastes nice and I hope it is creating a far better environment for my teeth to stay strong and healthy than traditional toothpastes.

T
Teresa
I bought this tooth paste to be

I bought this tooth paste to be healthier

M
Mary-Ann D.
Great mineral toothpaste

Love this alternative peppermint toothpaste, trying to get always from fluoride this has proved great, slightly expensive but worth it.

A
Alicia T.
Not sure

I started using Gutology toothpaste because I had a sensitive tooth. The pain wasn't getting any better. So, I visited my dentist. Apparently I've got exposed nerve, and I was prescribed some sensitive toothpaste. The sensitivity hasn't completely gone yet!

A
Alison C.
If unsure give it a go

I have problems with my gums from time to time they flare up and are quite tender. If I have a flare up when I visit the dentist it is an excuse for them to see me every 3 months. I don’t like fluoride in my toothpaste so when I saw that this toothpaste didn’t contain any I thought I would give it ago. The price put me off a little so if you could sell sample tubes at a cheaper price just so people could try it that would be a good Idea. I tried it at the price you sell it for because I thought it’s cheaper than all those visits to the dentist but some people can’t even afford the dentist so it maybe worth thinking about. On trying it I first noticed my mouth felt fresher, my teeth felt smooth and looked shiny . This feeling lasted throughout the day. After a couple of days my gums felt firm and my teeth actually stronger. I mentioned it to my son who tried it and now he’s converted. I’m waiting for the new mouthwash to arrive. I’m not sure when my next dentist appointment is but it will be interesting to hear what they say.

D
Daiana O.
Amazing product

50 years old, gum disease, didnt used the normal supermarket tooth paste cause heavy metal and fluoride. I ve bought GUTOLOGY and every problem I got is gone. We are using it ( my children aswel) 2 x per day, with dentist compliments.

F
Flo
Not sure yet

Not sure yet. My gums are really sore since I've started using this toothpaste. Might b| down to me brushing too hard. ATM not quite sure what to think.

A
Anthony

love it

L
Linda

Love this

M
Maria

I have tried a different toothpaste but I had to come back to you. It is excellent. Thank you😁

L
Lauren

My favorite toothpaste in the world.

R
Rebecca R.

Love this tooth paste. Teeth looked whiter and brighter within a few weeks

C
Claire

Great teeth protection with the whitening effect.

A
Anonymous
thank you gutology

love it, no downsides, bought the set with the floss and scraper and they work a treat too- so nice to use a plastic free floss. have noticed better breath for longer and the toothpaste has a nice flavour which isnt too overpowering.

M
Mr s.
I’ve only been using this product for a few days

I’ve only been using this product for a few days but I think I’ve noticed a slight difference in the smoothness of my teeth .
It seems to getting at the tartar that other toothpastes haven’t touched
I will continue and look forward to cleaner teeth

M
Mary L.
Always amazing

Always amazing. Clean, fresh and safe. Thank you. 😍

G
Gary

Been using for over a year. Great toothpaste albeit a bit pricey

B
BrambleLoves
Great product

Great product. Tastes is pleasant for me, but children think its too minty (Perhaps natural lemon (?)) Paste is thick and feels like it will go along way, so hopefully works out to be good value in the end.

B
BrambleLoves
The product is great. travel size is too small for the cost

The product is great. Teeth feel very clean and taste of paste is pleasant. The travel size 15ml is very expensive and I would rather buy a 100ml instead, if you made that. I did also buy the full size and that is great. the paste is very thick, so you only need a tiny amount. I'm hopeful it will be good value for money.

A
Ara H.
I use this every day - effective

I use this every day and it feels like it is doing useful work on the enamel and bacteria. I wouldn't go near the conventional pharmacy toothpastes with fluoride and this feels more effective than many of the health shop toothpastes. Recommend

A
Annette M.k.
Have been using this toothpaste for a month now I

Have been using this toothpaste for a month now I wish I heard about this sooner no more waking during the night with a cough due to a very dry mouth. Due to there other bran I was using. Gutology is the best brand I have use no more dry month are stomach issues.

A
Alan K.

taste good

S
Sarah

Minty and teeth feel clean!

Have concerns? That's okay. You can find all your urgent answers right here.

  • Is this toothpaste worth the price?

    Absolutely and here’s why:

    At 120ml, Gutology’s toothpaste is significantly bigger than many leading natural alternatives, which often come in 75ml tubes. That means more value per use.

    We use biomimetic hydroxyapatite a fluoride-free mineral that mirrors the natural structure of enamel and is studied for its role in supporting surface mineral balance.

    Stick with it and save. Our subscription model rewards consistency with better pricing no commitment, cancel anytime.

  • Do you test for heavy metals?

    Your health is our priority. Every batch is independently tested for heavy metals using ICP-MS (Inductively Coupled Plasma Mass Spectrometry) one of the most advanced and sensitive detection methods available.
    We test for critical elements including lead, arsenic, mercury, and cadmium, all of which are consistently below detectable limits.
    We also screen for other trace elements such as nickel, chromium, cobalt, and zinc and confirm that all results fall well within the EU and UK’s strict safety thresholds for daily exposure.
    These results are reviewed by our quality team to ensure the highest standards of purity and safety.

  • Is this product vegan and cruelty-free?

    Yes, this has been requested by many nutritionists that we work with. We've achieved this by using a vegetable sourced glycerine in our formulation. It is also 100% cruelty-free.

  • Allergies

    You are responsible for carefully reading any ingredients listed on our website and/or on any packaging, labels and/or leaflets to avoid the risk of allergic or other adverse reactions.

    For more information on allergies: click here.

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